Table 4.
Results from the meta-analysis.
| Exposition | Group (Number of studies) | Type of study | OR/RR (95% CI) | I2 |
|---|---|---|---|---|
| 25(OH)D | All (n = 29) | Case-control | 0.65 (0.56–0.76) | 40.87% |
| All (n = 4) | Cohort | 0.85 (0.74–0.98) | 3.56% | |
| ER+ (n = 5) | Case-control | 0.98 (0.85–1.13) | 0% | |
| ER– (n = 5) | Case-control | 0.86 (0.64–1.15) | 15.60% | |
| Postmenopausal (n = 19) | Case-control | 0.74 (0.59–0.93) | 13.16% | |
| Postmenopausal (n = 3) | Cohort | 1.15 (0.59–2.23) | 8% | |
| Premenopausal (n = 9) | Case-control | 0.63 (0.49–0.80) | 8.37% | |
| Dietary vitamin D | All (n = 8) | Case-control | 0.91 (0.72–1.17) | 30.73% |
| All (n = 5) | Cohort | 1.00 (0.93–1.07) | 0% | |
| Postmenopausal (n = 4) | Case-control | 0.78 (0.68–0.90) | 0% | |
| Postmenopausal (n = 5) | Cohort | 0.95 (0.83–1.09) | 19.13% | |
| Premenopausal (n = 5) | Case-Control | 0.65 (0.52–0.82) | 0% | |
| Premenopausal (n = 3) | Cohort | 1.01 (0.86–1.18) | 0% | |
| Vitamin D supplements | All (n = 5) | Case-control | 0.78 (0.63–0.98) | 25.94% |
| All (n = 2) | Cohort | 1.06 (0.90–1.25) | 0% | |
| Total Vitamin D intake (dietary + supplements) | All (n = 4) | Case-control | 0.84 (0.68–1.05) | 18.65% |
| All (n = 2) | Cohort | 0.93 (0.86–1.02) | 0% | |
| Postmenopausal (n = 5) | Cohort | 0.94 (0.87–1.02) | 17.64% | |
| Premenopausal (n = 3) | Cohort | 0.90 (0.72–1.12) | 10.83% |