Table 2.
Median (range) number of inflammatory cells and fungal load per mm2 in the skin lesion sample biopsied at T1 of the 52 cats with sporotrichosis according to outcome of itraconazole treatment and positive serology for FIV or FeLV.
| Cells/yeasts | Median (range) number of cells/mm2 in the biopsied skin lesion | ||||||
|---|---|---|---|---|---|---|---|
| Total (n = 52) | Outcome (n = 52) | pa | FIV/FeLV (n = 48) | pa | |||
| TF (n = 15) | CC (n = 37) | Positive (n = 12) | Negative (n = 36) | ||||
| Neutrophils | 171.1 (29.6–381.0) | 139.5 (53.2–234.4) | 152.7 (47.6–239.2) | 0.785 | 119.4 (47.6–173.4) | 144.2 (87.4–239.2) | 0.021* |
| Macrophages | 131.0 (9.0–1576.0) | 121.6 (80.6–157.2) | 122.2 (65.4–175.2) | 0.317 | 105.6 (80.6–170.6) | 127.4 (65.4–175.2) | 0.938 |
| Lymphocytes | 29.6 (13–106.4) | 29.8 (14.0–106.4) | 29.6 (18.4–41.8) | 0.793 | 30.6 (18.0–40.0) | 25.8 (14.0–106.4) | 0.482 |
| Plasma cells | 13.8 (0–89.2) | 11.6 (0.6–46.8) | 15.6 (0–89.2) | 0.739 | 15.6 (3.8–33.0) | 11.0 (0–89.2) | 0.543 |
| Mast cells | 9.4 (0–28.2) | 7.7 (0.6–12.6) | 9.7 (0.8–20.8) | 0.443 | 8.5 (3.2–20.8) | 9.2 (0.6–15.2) | 0.858 |
| MGC | 0 (0–3.4) | 0 (0–0.2) | 0 (0–3.4) | 0.844 | 0 (0–0.2) | 0 (0–3.4) | 0.858 |
| Eosinophils | 0 (0–5.6) | 0 (0–1.8) | 0 (0–1.6) | 0.87 | 0 (0–1.2) | 0 (0–1.8) | 0.674 |
| Yeasts | 38.1 (0–1,274.8) | 745.5 (2.2–1,274.8) | 204.9 (0.8–928.0) | 0.002* | 717.1 (10.0–1,274.8) | 309.2 (0.8–864.0) | 0.095 |
MGC, multinucleated giant cells; n, number of cats; TF, treatment failure; CC, clinical cure; aMann-Whitney test. *Significant difference (p < 0.05).