Table 3.
Comparison of the number of inflammatory cells and yeasts per mm2 in the skin lesion sample biopsied in the first appointment before treatment with itraconazole (T1) and in the sample of the same lesion biopsied 5 to 11 weeks after the beginning of itraconazole treatment (T2) obtained from 22 cats.
| Cells | Number of cells/mm2 in the biopsied skin lesion | pa | |||
|---|---|---|---|---|---|
| T1 (n = 22) | T2 (n = 22) | ||||
| Median | Range | Median | Range | ||
| Neutrophils | 148.1 | 47.6–239.2 | 132.2 | 0.2–341.6 | 0.638 |
| Macrophages | 129.0 | 65.4–211.4 | 98.0 | 2.4–166.2 | 0.036* |
| Lymphocytes | 26.9 | 14–106.4 | 26.4 | 5.2–107.6 | 0.935 |
| Plasma cells | 11.6 | 0–89.2 | 9.3 | 0–140.8 | 0.858 |
| Mast cells | 9.4 | 0.6–20.8 | 5.0 | 0–27.2 | 0.338 |
| MGC | 0 | 0–3.4 | 0 | 0–2.4 | 1.0 |
| Eosinophils | 0 | 0–1.8 | 0 | 0–22.4 | 0.779 |
| Yeasts | 407.7 | 0.8–1,274.8 | 1.1 | 0–153.8 | <0.001* |
n, number of cats; MGC, multinucleated giant cells; aWilcoxon signed-rank test. *Significant difference (p < 0.05).