Table 1.

Comparison of evaluation matrices between the training and the out-of-sample test sets for each functional group-based model.

Models	Precision		Recall		F1-Score		Accuracy		MCC
	Training set	Test set	Training set	Test set	Training set	Test set	Training set	Test set	Training set	Test set
ICB	91.25	95.58	83.80	92.85	0.87	0.94	89.67	95.32	0.78	0.90
AMP	86.56	85.96	77.08	81.66	0.81	0.84	86.33	87.74	0.71	0.74
ACRI	100.00	100.00	0.80	63.63	0.89	0.78	95.23	92.00	0.87	0.76
SPI	97.52	96.43	79.66	81.81	0.88	0.88	91.90	92.55	0.83	0.84
HLP	86.07	92.30	86.66	80.00	0.86	0.86	89.39	89.47	0.78	0.78

The precision, recall and accuracy values are shown in percentages.

Abbreviations: ICB = Ion channel blocker; AMP = Antimicrobial peptide; ACRI = Acetylcholine receptor inhibitor; SPI = Serine protease inhibitor; HLP = Hemolytic protein.