Fig. 2.

Comparison of Imputation Methods Using ToxPi priority ranks. Mean ToxPi Rank Change between Imputed Simulated Data and Imputed Raw Data. Rank change was calculated by using the magnitude of difference between individual chemical ranks in the imputed raw data and the chemical ranks from each simulated dataset. Binomial, LLS, Maximum, and Mean show small magnitudes of change in rank. kNN shows a wider variation in rank change and therefore represents less stability in the method. Minimum value imputation and SVD present wider ranges in rank change, although the magnitude of change is smaller than kNN