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. 2018 Jun 12;17:94. doi: 10.1186/s12943-018-0843-8

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — HULC promotes liver cancer cell growth in vivo. a The photography of xenograft tumors from Balb/C null mouse injected with Hep3B cells transfected with pCMV6-A-GFP,pCMV6-A-GFP-HULC subcutaneously at armpit. b The xenograft tumors weight (gram) in the two groups indicated in left. Data were means of value from nine Balb/c mice, mean ± SEM, n = 7,*, P < 0.05;**, P < 0.01. c The xenograft tumors formation rate(%) in the two groups indicated in left. d Hematoxylin-eosin (HE) staining of xenograft tumors (original magnification× 100). And anti-PCNA and anti-k67 immunostainningin xenograft tumor samples. (original magnification× 100)