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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Stem Cells. 2018 Mar;36(3):349–362. doi: 10.1002/stem.2746

Figure 7. Toxicity of 5FU tested with H9 and RIV9 hPSCs.

Figure 7

(A) Table of half-maximal inhibitory doses for cytotoxicity (IC50) as determined from concentration-response curves with MTT assay and differentiation (ID50) with calcium assay. (B) Linear regression of RIV9 half-maximal inhibition of differentiation graphed against H9 half-maximal inhibition of differentiation. Both cell lines showed similar classification in predicting skeletal toxicity of 5FU. 5FU, 5-fluorouracil; MTT, 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenylterazolium bromide.