Subject area	Medicine
More specific subject area	Healthcare
Type of data	Tables
How data was acquired	The data acquired from 80 HIV-positive patients. Multidimensional Health Locus of Control (MHLC) Scale and Medical Outcome Study Short-Form Health Survey (MOS-SF-36) used to measure patients' HLC and QOL, respectively.
Data format	Raw, analyzed
Experimental factors	Convenience sampling method was used. Sample size calculation was done based on a mean formula with Ơ=0.22, z=1.96 and d=0.05.
Experimental features	Normal distribution was assessed by Kolmogorov–Smirnov test. Pearson and Spearman correlation coefficients were used to investigate the correlation between the study variables. To assess the variables affecting quality of life, multiple linear regression method applied for age, gender, education, disease duration, and health locus of control.
Data source location	Mashhad, Razavi Khorasan province, Iran
Data accessibility	Data are included in this article