Table 1.
Blood glucose measurements after central infusion (mg/dL) | ||||
---|---|---|---|---|
Baseline | 90 min | 1 day | 7 days | |
Sham + Veh | 176 ± 7 | 233 ± 11* | 183 ± 8 | 200 ± 11 |
Sham + IGF-1 | 165 ± 6 | 210 ± 10* | 171 ± 11 | 163 ± 7 |
CCI + Veh | 187 ± 9 | 229 ± 9* | 203 ± 17 | 192 ± 16 |
CCI + IGF-1 | 179 ± 9 | 231 ± 12* | 170 ± 9 | 189 ± 11 |
Blood glucose was measured before sham or controlled cortical impact (CCI) injury, and at several time points post-injury in nonfasted mice. Blood glucose levels were significantly higher at 90 min after surgical procedures compared to all other time points, independent of treatment and injury status (*p < 0.05). Data are presented as mean ± SEM (n = 9 sham-injured/treatment and n = 19 CCI-injured/treatment).
Veh, vehicle; IGF-1, insulin-like growth factor-1; SEM, standard error of the mean.