Table 3.
Haploidentical vs HLA-matched sibling | Offspring vs HLA-matched sibling | |||||
---|---|---|---|---|---|---|
HR (95% CI) | P | Probability, % | HR (95% CI) | P | Probability, % | |
Acute GVHD II-IV at day 100 | 1.03 (0.78-1.35) | .86 | 32 vs 26 | 0.65 (0.44-0.97) | .034 | 16 vs 23 |
Acute GVHD III-IV at day 100 | 1.05 (0.64-1.73) | .84 | 12 vs 10 | 0.48 (0.25-0.92) | .028 | 5 vs 9 |
Chronic GVHD at 2 y | 0.63 (0.48-0.82) | <.001 | 42 vs 51 | 0.42 (0.30-0.58) | <.001 | 28 vs 46 |
Nonrelapse mortality at 2 y | 1.14 (0.77-1.69) | .52 | 15 vs 13 | 1.48 (1.05-2.09) | .025 | 21 vs 17 |
Relapse at 2 y | 1.01 (0.80-1.26) | .97 | 37 vs 37 | 1.17 (0.95-1.45) | .14 | 45 vs 41 |
Leukemia-free survival at 2 y | 1.04 (0.85-1.26) | .70 | 48 vs 50 | 1.27 (1.06-1.51) | .008 | 34 vs 42 |
Overall survival at 2 y | 1.00 (0.81-1.24) | .99 | 61 vs 61 | 1.32 (1.10-1.59) | .003 | 44 vs 51 |
Bold values represent statistical significance.