Figure 1.

Automatically identified cortical layers on the BigBrain displayed on three orthogonal planes. The brain was sectioned coronally and reconstructed to create a 3D isotropic volume at 20 μm. Cortical intensity profiles (zoomed insert), perpendicular to the cortex, were extracted at all vertices on the surface and used to identify continuous cortical layers. On the gray-scale histological images, minimum intensity pixels are white, maximum are black.