Table 1.
Comparison of 15O-gas PET and 99mTc-ECD SPECT values in MCA ROI of the precentral region in 20 cerebral hemispheres of 10 healthy subjects as controls and in 19 affected cerebral hemispheres of 19 patients.
| Controls | Patients | p | |
|---|---|---|---|
| (n = 20) | (n = 19) | ||
| CBF (ml/100 g/min) | <0.0001 | ||
| Mean | 46.7 | 34.0 | |
| SD | 4.6 | 2.8 | |
| 95% CI | 37.5 to 55.9 | 27.9 to 40.1 | |
| CBV (ml/100 g) | <0.0001 | ||
| Mean | 3.74 | 5.50 | |
| SD | 0.59 | 0.30 | |
| 95% CI | 2.47 to 5.01 | 4.85 to 6.15 | |
| CMRO2 (ml/100 g/min) | 0.3185 | ||
| Mean | 3.50 | 3.31 | |
| SD | 0.55 | 0.27 | |
| 95%CI | 2.32 to 4.68 | 2.73 to 3.89 | |
| OEF (%) | <0.0001 | ||
| Mean | 42.6 | 54.7 | |
| SD | 4.3 | 2.6 | |
| 95%CI | 33.5 to 51.8 | 49.2 to 60.2 | |
| RCVCRhypocap (%/mmHg) | 0.2021 | ||
| Mean | −0.14 | −0.77 | |
| SD | 0.47 | 2.24 | |
| 95%CI | −1.12 to 0.86 | −5.26 to 3.70 | |
PET: positron emission tomography; 99mTc-ECD: technetium-99 m-labeled ethyl cysteinate dimer; SPECT: single-photon emission computed tomography; MCA: middle cerebral artery; ROI: region of interest; CBF: cerebral blood flow; SD: standard deviation; CI: confidence interval; CBV: cerebral blood volume; CMRO2: cerebral metabolic rate of oxygen; OEF: oxygen extraction fraction; RCVCRhypocap: relative cerebrovascular contractile reactivity to hypocapnia.