Oligodendrocyte survival in the intragyral white matter of the first
and second parasagittal gyri and the periventricular white matter in
the sham control (n = 9), ischemia-normothermia (n = 8),
ischemia-48 h hypothermia (n = 8), and ischemia-72 h hypothermia
(n = 8) groups. (a) Ischemia was associated with a significant
reduction in oligodendrocyte survival in all white matter regions
with a partial improvement in both hypothermia groups in all
regions, which remained significantly lower than sham control. Data
are mean ± SEM, *p < 0.05 vs. sham control,
#p < 0.05 vs. ischemia-normothermia. (b)
Photomicrograph of Olig-2 positive labelling in the intragyral white
matter of the first parasagittal gyrus (A, D, G, J), the second
parasagittal gyrus (B, E, H, K) and the periventricular white matter
(C, F, I, L) in the sham control (A–C), ischemia-normothermia (D–F),
ischemia-48 h (G–I), and ischemia-72 h (J–L) groups. Scale bar
200 µm.