Fig. 9.

In Vivo Efficacy of Select Compounds. (A) Hyperalgesia was induced by intraplantar injection of CFA and thermal latencies were measured in mice following inhibitor administration (20 mg/kg, i.p.). n = 6-9 per group. **p < 0.01, ***p < 0.001 versus vehicle controls by one-way ANOVA with Dunnett post-hoc test. (B) Thermal latencies of wild-type (WT) and FABP5 KO mice following administration of 3 (40 mg/kg, i.p.). n = 6. ns indicates no significant difference, **p < 0.01 by two-ANOVA with Bonferonni post-hoc test. All data are presented as mean ± standard error.