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. Author manuscript; available in PMC: 2018 Jun 13.
Published in final edited form as: Biomaterials. 2016 Apr 1;97:85–96. doi: 10.1016/j.biomaterials.2016.03.039

Table 1.

Schematic representations of biomimetic NP, which exhibited similar physical properties of antigen loading, hydrodynamic diameter, and zeta potential in water.

Nomenclature −/− −/OVA −/OVA+CpG MPLA/OVA CpG/OVA MPLA/OVA+CpG
Schematic graphic file with name nihms788473t1.jpg graphic file with name nihms788473t2.jpg graphic file with name nihms788473t3.jpg graphic file with name nihms788473t4.jpg graphic file with name nihms788473t5.jpg graphic file with name nihms788473t6.jpg
Description Blank surface, empty interior Blank surface, OVA-loaded Blank surface, OVA and CpG Inside MPLA on surface, OVA inside CpG on surface, OVA inside MPLA on surface, OVA and CpG inside
Antigen Loading (μg/mg NP) n/a 54.0 60.2 48.0 60.5 41.0
Diameter (nm) 216.0 +/− 82.1 238.8 +/− 94.3 231.5+/− 99.1 263.7+/− 111.6 210.8+/− 103.7 298.0 +/− 114.2
Zeta potential (mV) −16.0 +/− 4.9 −11.1 +/− 5.3 −14.4 +/− 4.6 −17.3+/− 5.7 −14.5 +/− 5.9 −16.3+/− 4.2