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. 2018 Mar 28;472(6):1021–1028. doi: 10.1007/s00428-018-2336-y

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Quantification results of LAP (TGFβ1)⁺ immune cells. In control GCs, areas with the densest distribution were analyzed. a The number of LAP (TGFβ1)⁺ immune cells are larger in Ly-rich GCs than in control GCs. Box-whisker plots. Vertical line, the number of cells in one unit area (one lattice in a × 400 field, 0.0625 mm²). P values tested by Mann-Whitney U test. b, c Results of correlation analyses. The number of LAP (TGFβ1)⁺ immune cells correlated strongly with that of CXCR3⁺ cells (b), and weakly with FoxP3⁺ T_reg cells (c) in all GCs. Open circles, Ly-rich GCs. Black boxes, control GCs. Vertical line, the number of immunoreactive immune cells in one unit area (one lattice in a × 400 field, 0.0625 mm²). Statistical analysis by Spearman’s test