Table 2.

Dosing schemes recommended by the manufacturer

Drug	Renal status (CLCR [mL/min])	Dose				PB (%)
		mg	mg/kg	mg/24 h	Dosing pattern
Telavancin	> 50		10		od	90
	30–50		7.5		od
	< 30		Not indicated
Dalbavancin	≥ 30 or hemodialysis	1500			Single	93
		1000 LD, 500 MD			ow
	< 30 and no hemodialysis	1000			Single
		750 LD, 375 MD			ow
Oritavancin	≥ 30	1200			Single	85
	< 30 or hemodialysis	No data available
Vancomycin	> 100			1500–2000	2–4 doses/day	30–55
	100–70			1000–1500	2–3 doses/day
	70–30			500–1000	1–2 doses/day
Teicoplanin	> 80		6		Bid for 36 h, then od	87.6–90.8
			12		Bid for 36–60 h, then od
	80–30		6 LD, 3 MD		LD bid for 36 h, then od; from day 4 MD od or LD every second day
			12 LD, 6 MD		LD bid for 36–60 h, then od; from day 4 MD od or LD every second day
	< 30 or hemodialysis		6 LD, 2 MD		LD bid for 36 h, then od; from day 4 MD od or LD every third day
			12 LD, 4 MD		LD bid for 36–60 h, then od; from day 4 MD od or LD every third day

bid twice daily, CL_CR creatinine clearance, LD loading dose, MD maintenance dose, PB protein binding, od once daily, ow once weekly