Table 3.

Genetic counseling results

Characteristic	Control strategy (n = 292)	Intervention strategy (n = 489)	P value
Genetic counselor consulted	41 (14%)	67 (14%)	0.89h
Diagnosis after genetic testing
Yes	35 (12%)	46 (9.4%)	0.25h
Familial colorectal cancera	26	32
Lynch syndrome	3	2
Lynch like syndrome	1	0
Polyposis syndrome	5e	3f
Unknown yet, but definite diagnosis	0	9g
No	6 (2.1%)	17 (3.5%)
Syndrome ruled out	5	16
Wrong referral indication	1	1
Unknown yetb	0	4 (0.8%)
Colonoscopy screening/surveillance recommendation
Yes	35 (12%)	46 (9.4%)	0.25h
For patient	3	3
For patient and relativesc	14	18
For relativesc	18	16
For patient and possibly relativesd	0	9

^aDefined as a familial risk of CRC, without a known genetic cause, for which screening or surveillance recommendations are given

^bGenetic testing ongoing, unknown if a genetic or familial diagnosis will be made

^cColonoscopy screening and/or surveillance recommendations for relatives included: Colonoscopy surveillance 1×/5 year from the age of 37, 38, 40 or 45: n = 51, Colonoscopy screening at the age of 45, 50, 55 or 65: n = 14, Colonoscopy surveillance 1×/2 year from the age of 25: n = 1

^dGenetic testing ongoing that will certainly result in a genetic or familial diagnosis

^eIncluding three patients with serrated polyposis syndrome, two with polyposis of unknown origin

^fIncluding one patient with polyposis of unknown origin, one with MUTYH associated polyposis and one with serrated polyposis syndrome

^gGenetic test result unknown yet (either Lynch syndrome or FCC in eight and genetic or non-genetic polyposis in one)

^h2-Sided chi square test