Table 2. Characteristics of included studies comparing SLE with and without vertebral fractures.
Study | Setting |
Ethnicity | SLE patients with vertebral fractures | SLE patients without vertebral fractures | Menstrual status in SLE | GCT dose | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total | Age* | Female | Male | Total | Age* | Female | Male | Pre | Post | With VF | Without VF | |||
Borba 2005 | Brazil | Mixed | 15 | 28 | 15 | 0 | 55 | 32 | 55 | 0 | NR | NR | 15.3± 12.7 mg/day | 15.7±13.1 mg/day |
Mendoza-Pinto 2009 | México | Mixed | 53 | 50 | 53 | 0 | 157 | 41 | 157 | - | 106 | 104 | Mean cumulative dose 25.3 ± 26 g/day | Mean cumulative dose 17.2±18.2 g/day |
Li 2009 | China | Asian | 31 | 55 | 31 | 0 | 121 | 46 | 121 | - | 48 | 104 | Median dose 5.0 (3.1, 8.4) mg/day |
Median dose 6.4 (4.8, 8.2) |
Furukawa 2013 | Japan | Asian | 26 | 40 | 26 | 0 | 26 | 50 | 26 | - | 33 | 19 | 7.9 ± 4.5 mg/day | 8.9 ±5.2 mg/day |
Bonfá 2015 | Brazil | NR | 64 | 36 | 64 | 0 | 147 | 32 | 147 | 0 | 211 | 0 |
Cumulative dose 28.8±20.8 g |
Cumulative dose 28.5±22.7 g |
GCT = glucocorticoid therapy; g = grams; mg = milligrams; VF = vertebral fracture
* = mean
NR = Not reported