Table 4. List of significantly altered miRNA expressions in acute brucellosis cases.

	Chronic vs Control			Acute vs Control			Chronic vs Acute
miRNA	Fold change	Fold regulation	P value*	Fold change	Fold regulation	P value*	Fold change	Fold regulation	P value*
hsa-miR-939-5p	-	-	-	5.64	5.64	0.0782	0.18	-5.64	0.0782
hsa-miR-6724-5p	1.85	1.85	0.6528	28.13	28.13	0.0092	0.07	-15.21	0.0244
hsa-miR-6125	1.38	1.38	0.3405	2.87	2.87	0.0027	0.48	-2.08	0.0152
hsa-miR-6075	-	-	-	9.40	9.40	0.0303	0.11	-9.40	0.0303
hsa-miR-5006-5p	-	-	-	2.03	2.03	0.3559	0.49	-2.03	0.3559
hsa-miR-494	1.87	1.87	0.1288	4.57	4.57	0.0006	0.41	-2.44	0.0283
hsa-miR-4746-3p	1.87	1.87	0.3506	10.54	10.54	0.0311	0.18	-5.65	0.1253
hsa-miR-4665-3p	-	-	-	2.89	2.89	0.1723	0.35	-2.89	0.1723
hsa-miR-4507	1.38	1.38	0.7716	5.37	5.37	0.0608	0.26	-3.89	0.1322
hsa-miR-4459	1.74	1.74	0.2177	3.99	3.99	0.0006	0.44	-2.30	0.0739
hsa-miR-4430	1.74	1.74	0.3506	23.90	23.90	0.0106	0.07	-13.77	0.0281
hsa-miR-4281	1.87	1.87	0.5650	6.00	6.00	0.0400	0.31	-3.21	0.1870
hsa-miR-3653	1.40	1.40	0.7411	24.11	24.11	0.0257	0.06	-17.28	0.0400
hsa-miR-342-3p	0.98	-1.02	0.9800	3.48	3.48	0.2577	0.28	-3.55	0.2463
hsa-miR-3135b	1.81	1.81	0.5380	13.81	13.81	0.0247	0.13	-7.61	0.0958
hsa-miR-2861	1.36	1.36	0.4150	3.10	3.10	0.0028	0.44	-2.28	0.0161
hsa-miR-1587	1.89	1.89	0.3963	3.60	3.60	0.1031	0.53	-1.90	0.0331
hsa-let-7b-5p	1.76	1.76	0.5515	7.74	7.74	0.0893	0.23	-4.41	0.2377

*P values were calculated using an independent samples t-test.