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. 2018 Jun 13;13(6):e0197319. doi: 10.1371/journal.pone.0197319

Table 2. Fungal pathogen and Candida DNA detection rates from microbial culture, real-time PCR analysis, and its statistical significance.

Patients with cirrhosis (n = 135) Control patients without cirrhosis (n = 26)
Sample material No. of samples Culture positive (%) PCR positive (%), median copies/ml (range) P value culture vs. PCR No. of samples Culture positive (%) PCR positive (%), median copies/ml (range) P value culture vs. PCR P value PCRcirrhosis vs. PCRcontrol
Blood n = 135 n = 1 (0.7%) n = 1a (0.7%), 3.0x101 n = 26 n = 0 (0%) n = 0 (0%)
Ascites n = 92 n = 0 (0%) n = 1 (1.1%), 1.3x101
Duodenal fluid n = 54 n = 36 (66.7%) n = 44b (81.5%), 3.8x105 0.123 n = 26 n = 12 (46.2%) n = 16c (61.5%) 1.2x105 0.404 0.096
(2.3x102-6.3x109) (2.5x102-2.4x107)

a1/1

b34/36

c12/12 positive PCR results confirming microbial culture