Table 3. Comparison of expression of autophagy markers LC3B and p62 in a primary resected EAC cohort and a subcohort of neo-adjuvant chemotherapy (nCTX) treated EAC cases with paclitaxel containing regimens.
Significance was set to 0.05. Statistically significant p-values are shown in bold.
LC3B dots | Treatment | Total | |
Primary Resected | nCTX | ||
Low | 95 (83.3%) | 19 (67.9%) | 114 (80.3%) |
High | 19 (16.7%) | 9 (32.1%) | 28 (19.7%) |
Total | 114 | 28 | 142 |
p-value = 0.108 | |||
p62 dots | Treatment | Total | |
Primary Resected | nCTX | ||
Low | 95 (83.3%) | 9 (32.1%) | 104 (73.2%) |
High | 19 (16.7%) | 19 (67.9%) | 38 (26.8%) |
Total | 114 | 28 | 142 |
p-value < 0.001 | |||
p62 cytoplasmic | Treatment | Total | |
Primary Resected | nCTX | ||
Low | 86 (75.4%) | 12 (42.9%) | 98 (69.0%) |
High | 28 (24.6%) | 16 (57.1%) | 44 (31.0%) |
Total | 114 | 28 | 142 |
p-value < 0.001 | |||
p62 nuclear | Treatment | Total | |
Primary Resected | nCTX | ||
Low | 58 (50.9%) | 16 (57.1%) | 74 (52.1%) |
High | 56 (49.1%) | 12 (42.9%) | 68 (47.9%) |
Total | 114 | 28 | 142 |
p-value = 0.674 | |||
p62 dots-cyto | Treatment | Total | |
Primary Resected | nCTX | ||
Low | 76 (66.7%) | 4 (14.3%) | 80 (56.3%) |
High | 38 (33.3%) | 24 (85.7%) | 62 (43.7%) |
Total | 114 | 28 | 142 |
p-value < 0.001 | |||
LCB/p62 | Treatment | Total | |
Primary Resected | nCTX | ||
LL | 66 (57.9%) | 3 (10.7%) | 69 (48.6%) |
LH | 29 (25.4%) | 16 (57.1%) | 45 (31.7%) |
HL | 10 (8.8%) | 1 (3.6%) | 11 (7.7%) |
HH | 9 (7.9%) | 8 (28.6%) | 17 (12.0%) |
Total | 114 | 28 | 142 |
p-value < 0.001 |