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IgG response in sera of CD64 Tg mice immunized with dengue poly‐immunoglobulin G scaffold (D‐PIGS). (a) Kinetics of the cEDIII‐specific IgG response in sera after each immunization; 1 : 1000 serum dilution was used. Shown are the means ± SE for 5 mice per group. (b) Endpoint titres induced by D‐PIGS determined in pooled sera from five mice at equal ratios. (c and d) IgG1 and IgG2a endpoint titres in mice immunized with D‐PIGS (determined as in b).
