Figure 1.

Schematic of mouse model of glioblastoma resection and recurrence. Tumors xenografts were implanted and allowed to grow for several days as monitored by bioluminescent imaging (BLI). Established tumors were then surgically resected under fluorescent guidance leaving positive tumor margins. Drug-loaded polymer scaffolds were then implanted into the surgical cavity and the wound was sealed. Post-treatment tumor growth was then monitored with BLI.