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. Author manuscript; available in PMC: 2018 Jun 13.
Published in final edited form as: Mol Pharm. 2018 Feb 2;15(3):1309–1318. doi: 10.1021/acs.molpharmaceut.7b01114

Table 2.

Statistical Analysis by Proportional Hazard Ratio (Adjusted for Tumor Size), Estimated Hazard Ratios, and 95% Confidence Intervals for Overall and Progression Free Survival Rates Across Treatment Groups.

Treatment Group Overall Survival Progression Free Survival
Hazard Ratio (95% CI) P-value Hazard Ratio (95% CI) P-value
No Treatment 1 - 1 -
Ace-DEX/blank 0.81 (0.20–3.27) 0.766 0.74 (0.19–2.86) 0.661
Ace-DEX/10DXR 0.09 (0.02–0.46) 0.004 0.04 (0.01–0.25) 0.001
PLA/blank 0.46 (0.12–1.75) 0.254 0.41 (0.11–1.59) 0.200
PLA/10DXR 0.16 (0.03–0.85) 0.032 0.09 (0.02–0.54) 0.008