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. 2018 Aug;37(4):1313–1322. doi: 10.1016/j.clnu.2017.05.030

Table 3.

The association of intakes of sugars from liquids, sugars from solids, free sugars and non-free sugars (%TEI) and individual components of the metabolic risk z score using multiple linear regression; The Fenland Study, UK (n = 9768).

Sugars from liquids Sugars from solids Free sugars Non-free sugars
Mean (range), %TEI 2.9 (0–36.0) 20.6 (2.4–56.5) 12.0 (0.5–46.4) 11.5 (0.6–54.6)
per 10%TEI
Waist circumference (cm) 0.28 (−0.15,0.71) −0.21 (−0.44,0.01) 0.15 (−0.13,0.43) −0.32 (−0.60,−0.05)
Systolic blood pressure (mmHg) 1.81 (0.73,2.89)* −0.07 (−0.64,0.49) 0.43 (−0.27,1.12) 0.22 (−0.47,0.90)
Diastolic blood pressure (mmHg) 1.29 (0.57,2.02)* −0.28 (−0.66,0.10) 0.31 (−0.15,0.77) −0.18 (−0.63,0.28)
2 h plasma glucose (mmol/l) 0.16 (0.04,0.28) −0.08 (−0.15,−0.02) 0.07 (−0.01,0.15) −0.13 (−0.20,−0.05)*
ln Fasting insulin (ρmol/l) 0.04 (0.02,0.08)* −0.01 (−0.03,0.01) 0.05 (0.02,0.07)* −0.05 (−0.07,−0.02)*
HDL cholesterol (mmol/l) −0.04 (−0.07,−0.02)* −0.04 (−0.05,−0.03)* −0.05 (−0.06,−0.03)* −0.03 (−0.05,−0.01)*
ln Triglycerides (mmol/l) 0.07 (0.01,0.13)* 0.01 (−0.02,0.02) 0.06 (0.04,0.09)* −0.02 (−0.05,0.00)

Values are β-coefficients (95% confidence intervals).

Adjusted for age, sex, years of education, income level, social class, smoking status, alcohol consumption (units/week), test site, PAEE, clinical history (self-reported hypertension or use of anti-hypertensive medication or self-reported hyperlipidaemia or use of lipid lowering medication), weight-loss diet, fibre (NSP) intake, plasma vitamin C measurement, non-sugar containing beverage intake (tea, coffee, artificially sweetened beverages), low-nutrient energy-dense food intake (buns, cakes, puddings, biscuits, pastries, chocolate and non-chocolate confectionary and ice-cream), BMI, total energy intake and mutually adjusted for sugars (Model 2).

Metabolic risk z score: derived by summing the z-scores of the following continuous indices: waist circumference, systolic blood pressure + diastolic blood pressure, 2 h plasma glucose, fasting insulin, inverted fasting HDL cholesterol, and triglycerides.

*Significant after correction for multiple testing, p ≤ 0.0017.

Abbreviations: C-Reactive Protein, CRP; Glycated Haemoglobin, HbA1c; Homeostasis Model Assessment of Insulin Resistance, HOMA-IR; Non-Starch Polysaccharide, NSP; Percent Total Energy Intake, %TEI; Physical Activity Energy Expenditure, PAEE.