Fig. 2.

(a) SNI elicited mechanical allodynia on 7 days and 14 days after surgery, and ketamine (10 mg/kg intraperitoneally) did not relieve mechanical allodynia. (b) SNI reduced sucrose preference on 14 days after surgery. (c) SNI or ketamine did not affect locomotor activity. SNI reduced the latency to first immobility (d) and increased the immobility time in the FST (e). The data are presented mean±SEM (n=10–12). FST, forced-swim test; SNI, spared nerve injury. *P<0.05, vs. the Sham+Sal group; ^#P<0.05, vs. the SNI+Sal group.