Figure 4. A selection of cross-sectional schematic diagrams of particle and ice behaviors in holes as depicted according to analysis of individual tomograms.

The relative thicknesses of the ice in the cross-sections are depicted accurately. Each diagram is tilted corresponding to the tomogram from which it is derived; i.e. the depicted tilts represent the orientation of the objects in the field of view at zero-degree nominal stage tilt. If the sample concentration in solution is known, then it has been included below the sample name. Black lines on schematic edges are the grid film. The cross-sectional characteristics depicted here are not necessarily representative of the aggregate. An asterisk (*) indicates that a Video of the schematic diagram alongside the corresponding tomogram slice-through video is included for the sample. A dagger (^†) indicates that a dataset is deposited for sample. A generic particle, holoenzyme EMDB-6803 (Yin et al., 2017), is used in place of some confidential samples (samples #40, 41, and 46).