Table 3.

Selected odds ratios (OR) and 95% confidence intervals (95%CI) for thyroid cancer reflecting a 10, 100, or 1000 ng/g change in analyte, stratified by birth cohort.

	Stratified by Birth Cohort			p_interaction
	1923–1932 49 cases, 98 controls	1933–1942 37 cases, 74 controls	1943–1957 22 cases, 44 controls

	OR (95% CI)	OR (95% CI)	OR (95% CI)
Total PCBs¹	0.92 (0.83–1.01)	0.94 (0.86–1.03)	1.25 (1.00–1.56)	0.04
Low-chlorinated¹	0.53 (0.23–1.21)	1.15 (0.81–1.63)	0.87 (0.49–1.56)	0.21
PCB 28¹	0.20 (0.03–1.49)	1.29 (0.78–2.14)	0.78 (0.26–2.32)	0.17
PCB 74²	0.77 (0.57–1.05)	0.90 (0.63–1.27)	1.33 (0.62–2.85)	0.42
Moderately-chlorinated¹	0.91 (0.81–1.02)	0.92 (0.82–1.03)	1.31 (1.01–1.70)	0.04
PCB 99²	0.78 (0.61–0.99)	0.86 (0.65–1.14)	1.57 (0.82–3.01)	0.14
PCB 105²	0.81 (0.55–1.20)	0.63 (0.34–1.17)	4.26 (0.96–19.0)	0.07
PCB 118²	0.94 (0.85–1.05)	0.92 (0.80–1.07)	1.28 (0.97–1.71)	0.11
PCB 138/158¹	0.73 (0.46–1.15)	0.78 (0.48–1.25)	4.54 (1.20–17.2)	0.04
PCB 146²	0.85 (0.65–1.11)	0.92 (0.73–1.16)	2.48 (1.10–5.58)	0.05
PCB 153¹	0.75 (0.50–1.12)	0.88 (0.63–1.22)	3.47 (1.18–10.2)	0.03
PCB 156²	0.75 (0.50–1.11)	0.87 (0.62–1.23)	2.16 (0.93–5.01)	0.08
PCB 170²	0.88 (0.75–1.05)	0.94 (0.82–1.06)	1.35 (0.98–1.85)	0.07
PCB 180¹	0.59 (0.28–1.24)	0.79 (0.46–1.37)	3.43 (0.92–12.7)	0.07
PCB 183²	0.74 (0.47–1.15)	0.73 (0.45–1.19)	4.00 (1.20–13.3)	0.03
PCB 187²	0.85 (0.69–1.04)	0.94 (0.80–1.11)	1.45 (0.94–2.23)	0.09
Highly-chlorinated²	0.87 (0.75–1.00)	0.95 (0.86–1.06)	1.10 (0.92–1.33)	0.13
PCB 194²	0.72 (0.43–1.20)	0.86 (0.58–1.27)	1.28 (0.68–2.43)	0.38
PCB 196/203²	0.55 (0.33–0.92)	0.81 (0.54–1.22)	1.57 (0.77–3.20)	0.06
PCB 199²	0.53 (0.31–0.90)	0.84 (0.56–1.24)	1.26 (0.65–2.43)	0.12
Thyroid-like¹	0.62 (0.38–1.02)	1.01 (0.73–1.40)	1.83 (0.63–5.28)	0.11
Dioxin-like²	0.95 (0.88–1.02)	0.94 (0.86–1.03)	1.16 (0.98–1.38)	0.07
Wolff 1A²	0.96 (0.80–1.16)	1.01 (0.91–1.12)	0.96 (0.82–1.12)	0.83
Wolff 1B²	0.91 (0.79–1.05)	0.93 (0.81–1.06)	1.19 (0.89–1.61)	0.26
Wolff 2A¹	0.71 (0.42–1.20)	0.70 (0.36–1.36)	4.05 (0.85–19.2)	0.10
Wolff 2B¹	0.78 (0.54–1.11)	0.83 (0.58–1.18)	2.92 (1.11–7.69)	0.04
Wolff 3¹	0.83 (0.66–1.05)	0.92 (0.76–1.11)	1.80 (1.04–3.12)	0.04
OC Pesticides
DDT Metabolites³	0.69 (0.49–0.98)	0.89 (0.66–1.20)	0.87 (0.57–1.31)	0.53
p,p′-DDE³	0.66 (0.45–0.97)	0.88 (0.64–1.21)	0.87 (0.56–1.35)	0.49
p,p′-DDT¹	0.84 (0.63–1.13)	0.96 (0.68–1.36)	0.74 (0.41–1.33)	0.72
o,p′-DDT²	0.79 (0.57–1.09)	0.90 (0.62–1.29)	0.72 (0.37–1.37)	0.79
Chlordane Metabolites²	0.81 (0.65–1.02)	0.88 (0.69–1.13)	1.78 (1.09–2.93)	0.02
trans-Nonachlor²	0.68 (0.47–0.98)	0.90 (0.61–1.31)	2.43 (1.11–5.34)	0.02
β-HCCH¹	0.28 (0.09–0.88)	0.94 (0.45–1.95)	0.82 (0.24–2.81)	0.21
HCB¹	0.63 (0.36–1.08)	0.90 (0.54–1.48)	0.87 (0.31–2.43)	0.62

Abbreviations: dichlorodiphenyldichloroethylene (DDE), dichlorodiphenyltrichloroethane (DDT), hexachlorocyclohexane (HCCH), hexachlorobenzene (HCB)

OR reflects 100-unit change

OR reflects 10-unit change

OR reflects 1000-unit change