Table 1.
Neurobehavioral tests assessed by domain and clinical trial years employed.
| YEARS 0-3 | YEARS 4-7 |
|---|---|
| ATTENTION | |
| Stroop word (strpwd) (↑) | Stroop word (strpwd) (↑) |
| Stroop color (strpcol) (↑) | Stroop color (strpcol) (↑) |
| Stroop color/word (strpcwd) (↑) | Stroop color/word (strpcwd) (↑) |
| WISC-III Digitspan (digspn) (↑) | WAIS-III digitspan (adigit) (↑) |
| — | WMS-III spatialspan (spsn) (↑) |
| Trailmaking A (trisasec)(↓) | Adult Trailmaking A (atriasec) (↓) |
| VISUAL-SPATIAL ACUITY | |
| Standard Reaction Time (SRTmean)(↓) | Standard Reaction Time (SRTmean)(↓) |
| WISC-III coding (coding) (↑) | WAIS-III digit symbol (adigsym) (↑) |
| WISC-III symbolsearch (symser) (↑) | WAIS-III symbolsearch ((asymb) (↑) |
| LEARNING & MEMORY | |
| RAVLT Tr1-Lsit A (rvlt1) (↑) | RAVLT Tr1-List A (rvlt1) (↑) |
| RAVLT Tr5-List A (rvlt5) (↑) | RAVLT Tr5-List A (rvlt5) (↑) |
| RAVLT Tr6-List B (rvlt6) (↑) | RAVLT Tr6-List B (rvlt6) (↑) |
| RAVLT Tr7 List A/post List B (rvlt7) (↑) | RAVLT Tr7 List A/post List B (rvlt7) (↑) |
| RAVLT Tr8 List A 20′ (rvlt8) (↑) | RAVLT Tr8 List A 20′ (rvlt8) (↑) |
| RAVLT Sum Trs1-5 (ravlttot) (↑) | RAVLT Sum Trs1-5 (ravlttot) (↑) |
| — | WMS-III vis repro immed (vireim) (↑) |
| — | WMS-III vis repro del (virede) (↑) |
| — | CMVT d-prime (CMVTdp) (↑) |
| EXECUTIVE FUNCTION | |
| Trailmaking B (trisbsec) (↓) | Adult Trailmaking B (atrlbsec) (↓) |
| — | WCST cats completed (wcsca) (↑) |
| — | WCST # correct (wcscorr) (↑) |
| MOTOR FUNCTION | |
| WRAVMA pegs-dom (pegdom) (↑) | WRAVMA pegs-dom (pegdom) (↑) |
| WRAVMA pegs-nondom (pegnd) (↑) | WRAVMA pegs-nondom (pegnd) (↑) |
| Finger Tapping dom (ftapd) (↑) | Finger Tapping dom (ftapd) (↑) |
| Finger tapping non-dom (ftapndo) (↑) | Finger tapping non-dom (ftapndo) (↑) |
Arrows depict direction of improved performance.
Abbreviations employed:
CVMT Continuous Visual Memory Test
RAVLT Rey Auditory Verbal Learning Test
WAIS-III Weschler Adult Intelligence Scale-III
WCST Wisconsin Card Sorting Test
WISC-III Weschler Intelligence Scale for Children-III
WMS-III Weschler Memory Scale for Adults-III
WRAVMA Wide Range Assessment of Visual Motor Abilities