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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Biomaterials. 2018 May 26;176:71–83. doi: 10.1016/j.biomaterials.2018.05.041

Fig. 1. Screening of the peptides to enhance AAV8 transduction without cytotoxicity in vitro.

Fig. 1

(A) Different concentrations of the peptides (0.001 mM and 0.01 mM) were first incubated with 1×108 vg of AAV8/luc at 4 °C for 2 h, and then added into 1×105 cells for 48 h. After that, the cytotoxicity of the peptides was measured using the MTT assay. (B) The transduction efficiency of the different AAV8 (1×104 vg per cell) and peptide complexes were tested in the HEK293 and Huh7 cell lines. *p < 0.05 compared to the AAV8 transduction alone group. All error bars represent the SD of the mean from at least a triplicate of experiments.