1.

基于MRI诊断的241例NSCLC患者的一般资料和单因素分析结果

Characteristics and univariate analysis of overall survival in 241 NSCLC patients with brain metastases diagnosed by constrast-enhanced MRI

Characteristics		n	MST (month)	1-year survival rate	2-year survival rate	P
MST: median survival time; KPS: karnofsky performance score; CEA: carcinoembryonic antigen. NSCLC: non-small cell lung cancer; MRI: magnetic resonance imaging.
Gender	Male	144	6.5	29.9	13.1	0.011
	Female	97	11.4	45.4	18.5
Age (yr)	> 65	64	6.0	26.6	13.6	0.067
	≤65	177	9.5	40.1	16.0
KPS	> 70	179	9.8	40.2	18.1	0.007
	≤70	62	6.8	25.8	7.3
Pathology	Adenocarcinoma	165	9.3	37.6	15.8	0.218
	Non-adenocarcinoma	76	6.0	34.2	13.9
Symptoms	Yes	17	5.6	17.6	5.9	0.022
	No	224	8.7	37.9	16.0
Tumor size	≥2 cm	30	4.9	26.7	8.3	0.058
	< 2 cm	211	8.8	37.9	16.4
Numbers	1-3	143	8.7	35.7	18.7	0.387
	> 3	98	8.5	37.8	10.0
CEA	≥40	71	9.2	35.2	16.5	0.499
	< 40	170	8.1	37.1	14.6
Tumor status in thoracic	Progression	182	6.8	25.8	6.0	< 0.001
	Stable	59	16.2	69.5	47.8
Tumor tatus intracalvarium	Progression	181	9.1	38.5	19.5	0.150
	Stable	60	9.1	38.5	19.5
Thoracic radiotherapy	Yes	24	11.5	41.7	12.5	0.667
	No	217	8.4	35.9	15.7
Chemotherapy	≥3 cycles	140	10.1	44.3	23.2	< 0.001
	< 3 cycles	101	6.2	25.7	3.0
Target therapy	Yes	67	13.6	61.2	32.1	< 0.001
	No	174	6.7	27.0	8.8