4.

CYP1A1 Ⅱe/Val位点与GSTM1联合基因型病例对照研究与肺癌危险性关系

Case–control studies for CYP1A1 Ⅱe/Val and GSTM1 combined gene polymorphism and lung cancer risk

Author	Year	GSTM1 genotype	CYP1A1 Ⅱe/Ⅱe genotype			GSTM1 genotype	CYP1A1 Val/Val genotype			GSTM1 genotype	CYP1A1 Ⅱe/Val & Val/Val genotype
			Case	Control	OR (95%CI)		Case	Control	OR (95%CI)		Case	Control	OR (95%CI)
Nakachi[12]	1993	+	19	57	1.00	+	1	3	1.00	+	14	29	1.00
		-	31	53	1.75 (0.89-3.47)	-	8	3	8.00 (0.58-110.27)	-	21	31	1.40 (0.60-3.27)
Nimura[18]	1997	+	27	45	1.00	+	7	5	1.00	+	15	29	1.00
		-	23	47	0.82 (0.41-1.63)	-	8	2	2.86 (0.42-19.65)	-	26	16	3.14 (1.30-7.58)
Qu[11]	1998	+	39	50	1.00	+	4	4	1.00	+	39	35	1.00
		-	59	56	1.35 (0.77-2.36)	-	6	3	2.00 (0.28-14.20)	-	43	38	1.02 (0.54-1.91)
Persson[13]	1999	+	17	20	1.00	+	3	4	1.00	+	10	20	1.00
		-	32	57	0.66 (0.30-1.44)	-	3	1	4.00 (0.27-60.32)	-	16	22	1.45 (0.54-3.94)
Hayashi[15]	2000	+	49	55	1.00	+	-	-	-	+	14	8	1.00
		-	71	76	1.05 (0.63-1.73)	-	-	-	-	-	22	9	1.40 (0.44-4.48)
Xue[14]	2001	+	27	42	1.00	+	4	2	1.00	+	21	25	1.00
		-	31	28	1.72 (0.85-3.48)	-	6	1	3.00 (0.20-45.24)	-	27	11	2.92 (1.18-7.26)
Zhang[17]	2002	+	8	21	1.00	+	4	3	1.00	+	16	12	1.00
		-	16	11	3.82 (1.25-11.69)	-	8	2	3.00 (0.35-25.87)	-	25	16	1.17 (0.44-3.11)
Quinones[16]	2004	+	29	41	1.00	+	-	-	-	+	53	23	1.00
		-	61	57	1.51 (0.83-2.75)	-	-	-	-	-	54	23	1.02 (1.08-2.03)
					Summary				Summary				Summary
		+			1.00	+			1.00	+			1.00
		-			1.28 (1.02-1.61)	-			3.18 (1.27-7.98)	-			1.45 (1.08-1.94)