1.
Baseline characteristics of study population (n=571)
| Variables | Patients without para L/T (n=505) | Patients with para L/T (n=66) |
| para L/T: paraneoplastic Leuko/thrombocytosis; EGFR: epidermal growth factor receptor. | ||
| Paraneoplastic thrombocytosis (n) | - | 26 |
| Paraneoplastic leukocytosis (n) | - | 50 |
| Leukothrombocytosis (n) | - | 10 |
| Age (mean in years) | 66.4 (55.9-66.9) | 65.4 (54.5-76.3) |
| Male (%) | 57 | 60.9 |
| Histology | ||
| Adeno (%) | 44.9 | 27.3 |
| Squamous cell (%) | 31.1 | 33.3 |
| Large cell (%) | 3.5 | 4.5 |
| Bronchoalveolar (%) | 1.2 | 4.5 |
| Adenosquamous (%) | 1.5 | 0 |
| Non-small, no defined histology (%) | 17.6 | 30.3 |
| Stage | ||
| Ⅰ (%) | 23.5 | 6.2 |
| Ⅱ (%) | 8.6 | 4.6 |
| Ⅲ (%) | 25.1 | 17 |
| Ⅳ (%) | 42.9 | 72.3 |
| EGFR status (proportion) | 4/51 | 1/9 |
| ALK mutation status (proportion) | 2/51 | 0/9 |
| Gross or microscopic necrosis (%) | - | 11.8 |
| Chemotherapy-administered (%) | 50.2 | 33 |