. 2011 Mar 20;14(3):233–238. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2011.03.09

2.

非小细胞肺癌组织和相应正常组织甲基化差异(n =78)

Methylation profiles in NSCLC tissues and matched normal tissues (n =78)

Gene	Methylation frequency [n (%)]		95%CI	P^*
Gene	Tumor tissues	Normal tissues	95%CI	P^*
^*Chi-square test or Fisher’s exact test; ^an =40.
DLEC1	32 (41.03)	3 (3.85)	2.207-126.864	< 0.001
RASSF1A	31 (39.74)	6 (7.69)	3.066-20.431	< 0.001
RARβ	24 (30.77)	7 (8.97)	1.809-11.236	0.001
hMLH1	13 (16.67)	4 (5.13)	1.149-11.911	0.037
FHITa	0 (0)	0 (0)	—	—
DLEC1+RASSF1A+RARβ+hMLH1	54 (69.23)	13 (16.67)	5.233-24.185	< 0.001