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. 2018 Jun 7;12:152. doi: 10.3389/fncel.2018.00152

Figure 5.

Figure 5

Effects of U0126, LMB and roscovitine on Ki-67 expression in the CA1 region following SE. (A) Representative double immunofluorescent images for Ki-67 positive astrocytes. SE increases nuclear Ki-67 expression in astrocytes. As compared to vehicle, U0126, LMB and roscovitine reduce the number of Ki-67 positive astrocytes following SE. Insert images are high magnification of rectangles in merge panels. Bar = 100 and 25 (inserts) μm. (B) Quantifications of the number of Ki-67 positive astrocytes. Open circles indicate each individual value. Horizontal bars indicate mean value. Error bars indicate SEM (*,#p < 0.05 vs. control and vehicle, respectively; n = 7, respectively).