3.

33例患者化疗前后EGFR基因突变状态变化与疗效的关系

The profile of EGFR gene mutation status of pre- and post-chemotherapy serum samples and its relation with efficacy of chemotherapy in 33 patients enrolled

Changes of EGFR mutation status of pre- and post-chemotherapy	Efficacy evaluation
	PR	SD	PD
PR: partial response; SD: stable disease; PD: progressive disease.
Negative→Negative	1 (20%)	7 (31.8%)	2 (33.3%)
Positive→Negative	0 (0%)	4 (18.2%)	1 (16.7%)
Negative→Positive	3 (60%)	6 (27.3%)	1 (16.7%)
Positive→Positive	1 (20%)	5 (22.7%)	2 (33.3%)
Total	5	22	6