3.
231例EGFR突变的患者的PFS的单因素分析
Univariate analysis of PFS in 231 EGFR mutation patients
| Variables | Median PFS (mon) | Range (mon) | P |
| PFS: progression-free survival. | |||
| Gender | 0.226 | ||
| Male | 15.1 | 11.8-18.3 | |
| Female | 16.3 | 13.5-19.1 | |
| Age (year) | 0.171 | ||
| < 65 | 15.2 | 12.9-17.4 | |
| > 65 | 17.6 | 14.3-20.9 | |
| Smoking characteristics | 0.139 | ||
| Yes | 13.9 | 10.6-17.2 | |
| No | 16.3 | 13.8-18.8 | |
| Histology | 0.411 | ||
| Adenocarcinoma | 15.7 | 13.7-17.7 | |
| Non-adenocarcinoma | 11.0 | 8.6-13.3 | |
| Brain metastasis | 0.014 | ||
| Yes | 11.7 | 10.2-13.1 | |
| No | 16.3 | 14.5-18.1 | |
| Liver metastasis | 0.856 | ||
| Yes | 15.1 | 9.7-20.4 | |
| No | 15.7 | 13.9-17.5 | |
| Mutation type | 0.142 | ||
| Exon 19 | 16.3 | 14.5-18.1 | |
| 21 L858R | 12.4 | 8.9-15.8 | |
| Treatment line | 0.006 | ||
| First line | 16.7 | 14.2-19.2 | |
| Second line and above | 12.4 | 9.6-15.2 | |
| ECOG score | 0.008 | ||
| 0-1 | 16.3 | 14.7-17.9 | |
| > 2 | 11.6 | 9.2-14.1 | |