7.

整合素对SBC3细胞粘附的调节作用。A：αv或α5整合素抗体部分阻断Ach对细胞粘附的刺激作用（^*P＜0.05），αv和α5或β1整合素抗体完全阻断Ach对细胞粘附的刺激作用（◆P＜0.01）。B：整合素抗体对Ach刺激的SBC3细胞粘附作用显微镜下表现（400×）。B1：Fn；B2：10^-4 M Ach；B3：10^-4 M Ach+5 μg/mL anti-αv整合素；B4：10^-4 M Ach+5 μg/mL anti-α5整合素；B5：10^-4 M Ach+5 μg/mL anti-αv+5 μg/mL anti-α5整合素；B6：10^-4 M Ach+5 μg/mL anti-β1整合素。

Integrin regulated cell adhesion. A: anti-αv integrin antibody or anti-α5 integrin antibody could partially block the effect of cell adhesion stimulated by Ach, anti-αv integrin combine with anti-α5 integrin or anti-β1 integrin fully blocked the influence of Ach on cell adhesion. B: The photos under microscope show the role of integrin antibody have an inhibitory effect of cell adhesion stimulated by Ach (400×). B1: Fn; B2: 10^-4 M Ach; B3: 10^-4 M Ach+5 μg/mL anti-αv integrin; B4: 10^-4 M Ach+5 μg/mL anti-α5 integrin; B5: 10^-4 M Ach+5 μg/mL anti-αv integrin+5 μg/mL anti-α5 integrin; B6: 10^-4 M Ach+5 μg/mL anti-β1 integrin.