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. 2015 Feb 20;18(2):92–97. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2015.02.08

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EFEMP1通过下调MMP-7的表达抑制肺癌细胞侵袭。A：EFEMP1转染肺癌细胞后，Western blot分析12 h、24 h MMP-7的表达，实时定量PCR分析MMP-7表达量变化；B：荧光素酶活性实验分析EFEMP1表达下调MMP-7报告质粒的荧光素酶表达。

EFEMP1 suppressed lung cancer cell invasion by downregulating MMP-7 expression. A: Western blot analysis of MMP-7 expression in A549 and H1299 cells at 12 h and 24 h after transfection with EFEMP1 or the control empty vector. MMP-7 expression was confirmed by real-time PCR; B: Luciferase activities of MMP-7 reporter construct were determined 24 h after transfection with EFEMP1. MMP-7: matrix metalloproteinase-7.