4.

MMP-7表达沉默后降低肺癌细胞的侵袭性。A：siRNA沉默后，Western blot检测MMP-7表达；B：siRNA沉默后，基质胶侵袭实验分析A549和H1299的侵袭性；C：MMP-7经siRNA沉默后，克隆形成实验检测A549和H1299的增殖能力。^*：P < 0.01 Student’s t-test。

Silence of MMP-7 expression decreased the invasiveness in lung cancer cells. A: MMP-7 expression was analyzed by Western blot 36 h after siRNA transfection in A549 and H1299; B: Cell invasion was analyzed by Matrigel assay 36 h after siRNA transfection; C: Colony formation of A549 and H1299 cells transfected with MMP-7 siRNA or the siRNA control. ^*: P < 0.01 Student's t-test.