1.
37例晚期非小细胞肺癌患者的基线特征
Basic characteristics of thirty-seven patients with advanced non-small cell lung cancer (NSCLC)
| Characteristics | n | Second-line (n=13) | Third-line and beyond (n=24) |
| Median age (year) | 52 | 52 | 51.5 |
| Gender | |||
| Male | 18 | 6 | 12 |
| Female | 19 | 7 | 12 |
| ECOG performance status | |||
| 0-1 | 32 | 11 | 21 |
| 2-3 | 2 | 0 | 2 |
| Unkown | 3 | 2 | 1 |
| Smoking history | |||
| Never | 21 | 7 | 14 |
| Former and current | 13 | 6 | 7 |
| Unkown | 3 | 0 | 3 |
| Histology | |||
| Adenocarcinoma | 29 | 11 | 18 |
| Large-cell carcinoma | 2 | 1 | 1 |
| Squamous cell carcinoma | 5 | 1 | 4 |
| Unkown | 1 | 0 | 1 |
| First-line therapy | |||
| Taxol-platinum | 15 | 5 | 10 |
| Vinorelbine-platinum | 9 | 4 | 5 |
| Gemcitabine-platinum | 10 | 3 | 7 |
| Others | 3 | 1 | 2 |
| Sencond-line therapy | |||
| Tyrosine kinase inhibitors | - | - | 10 |
| Docetaxel | - | - | 4 |
| Docetaxel-based | - | - | 5 |
| Others | - | - | 5 |
| Best response to first-line therapy | |||
| Partial response | 12 | 6 | 6 |
| Stable disease | 17 | 3 | 14 |
| Progressive disease | 6 | 3 | 3 |
| Unkown | 2 | 1 | 1 |