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原发灶与相应转移灶的EGFR基因突变状况

EGFR mutations in primary and corresponding metastatic tumors

Case	Histology	Primary lung tumor		Metastatic sites	Metastatic tumor
		Types of mutations	Mutation site		Types of mutations	Mutation site
ADC: adenocarcinoma; SQC: squamous cell carcinoma; ASC: adenosquamous carcinoma; LN: lymph node.
1	ADC	exon 21	2582 T>A	Subaortic LN	wild	wild
2	ADC	exon 21	2573 T>G	Brain	21 exon	2573 T>G
3	ASC	exon 21	2573 T>G	Subaortic LN	wild	wild
4	ADC	exon 21	2573 T>G	Lower paratracheal LN	wild	wild
5	ADC	exon 21	2573 T>G	Upper paratracheal LN	wild	wild
6	ADC	exon 21	2573 T>G	Lower paratracheal LN	21 exon	2573 T>G
7	ADC	exon 21	2573 T>G	Subcarinal LN	wild	wild
8	ADC	exon 21	2573 T>G	Lower paratracheal LN	21 exon	2573 T>G
9	ADC	exon 21	2573 T>G	Subaortic LN	21 exon	2573 T>G
10	ADC	exon 21	2573 T>G	Subaortic LN	21 exon	2573 T>G
11	ADC	exon 21	2573 T>G	Subcarinal LN	21 exon	2573 T>G
12	ADC	exon 21	2573 T>G	Subcarinal LN	21 exon	2573 T>G
13	ADC	exon 21	2573 T>G	Lower paratracheal LN	wild	wild
14	ADC	exon 21	2573 T>G	Lower paratracheal LN	wild	wild
15	ASC	exon 19	E746-A750	Lower paratracheal LN	19 exon	E746-A750
16	ADC	exon 19	E746-A750	Subcarinal LN	19 exon	E746-A750
17	ADC	exon 19	E746-A750	Upper paratracheal LN	19 exon	E746-A750
18	ASC	exon 19	E746-A750	Subaortic LN	19 exon	E746-A750
19	ADC	exon 19	E746-A750	Subaortic LN	19 exon	E746-A750
20	ADC	exon 19	E746-A750	Subcarinal LN	19 exon	E746-A750
21	ADC	exon 19	E746-A750	Subcarinal LN	wild	wild
22	ADC	exon 19	E746-A750	Lower paratracheal LN	19 exon	E746-A750
23	ADC	exon 19	E746-A750	Subaortic LN	19 exon	E746-A750
24	ADC	exon 19	E746-A750	Subcarinal LN	wild	wild
25	ADC	exon 19	E746-A750	Lower paratracheal LN	19 exon	E746-A750
26	SQC	exon 19	E746-A750	Subaortic LN	wild	wild
27	ADC	exon 19	E746-A750	Subcarinal LN	19 exon	E746-A750
28	ADC	exon 19	E746-A750	Subcarinal LN	wild	wild
29	ADC	exon 19	E746-A750	Upper paratracheal LN	19 exon	E746-A750
30	ADC	wild	wild	Supraclavicular LN	wild	wild
31	ADC	wild	wild	Supraclavicular LN	wild	wild
32	ADC	wild	wild	Brain metastases	wild	wild
33	ADC	wild	wild	Brain metastases	wild	wild
34	ADC	wild	wild	Upper paratracheal LN	wild	wild
35	ADC	wild	wild	Brain	wild	wild