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. 2018 May 20;21(5):389–396. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2018.05.06

2.

配对血液与肿瘤组织样本EGFR基因检测结果不一致病例

Inconsistent results of EGFR mutation detection in matched blood and tumor tissue specimen

Group Blood Tissue No. of sample
Pre-therapy group (n=13) 19Del T790M 19Del 2
L858R T790M L858R 1
L858R 19Del L858R 1
19Del L858R L858R 1
Wild type 20-INS 1
Wild type L858R 2
Wild type 19Del 5
Targeted therapy group (n=12) 19Del T790M 19Del 5
L858R T790M L858R 1
Wild type 19Del 1
Wild type L858R 3
Wild type 19Del L858R 1
Wild type 19Del T790M 1
Chemotherapy group (n=9) Wild type G719X 1
Wild type L858R 1
Wild type 19Del 4
Wild type 19Del T790M 3