3.

氨柔比星单药或联合方案治疗复发SCLC的研究

Single-agent amrubicin or combination chemotherapy for relapsed SCLC

Study	Phase	Dose (mg/m2)	Chemosensitivity	n	RR (%)	MST (month)
S: sensitive; R: resistant; AUC: area under the curve.
Kato[11]	Ⅱ	45, d1-d3	S	24	50.0	10.4
			R	10	60.0	6.8
Onoda[12]	Ⅱ	40, d1-d3	S	44	52.0	11.6
			R	16	52.0	10.3
Kaira[13]	Ⅱ	35, d1-d3	S	10	60.0	12.0
			R	19	36.8	11.0
Ettinger[14]	Ⅱ	40, d1-d3	S	0	-	-
			R	75	21.3	6.0
Hirose[15]	Ⅱ	30, d1-d3, carboplatin AUC=4	S	12	58.4	10.0
			R	15	15.4	5.0