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. 2012 Aug 20;15(8):465–470. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2012.08.03

1.

肺癌患者化疗不同时期EORTC QLQ-C30各领域得分比较(Mean±SD)

Compare of the scores for EORTC QLQ-C30 in different periods of chemotherapy (Mean±SD)

   Baseline After 2 cycles After 4 cycles F P
  *Compare with before chemotherapy and after 2 cycles, P < 0.05; Compare with after 2 cycles and after 4 cycles, P < 0.05;
  Compare with before chemotherapy and after 4 cycles, P < 0.05.
Functioning scales
  Physical 75.10±11.49 73.11±11.82 65.40±16.96△※ 7.015 0.001
  Role 66.00±23.00 60.66±19.00 50.00±21.84△※ 7.680 0.001
  Emotion 63.32±24.11 61.66±21.24 47.63±18.53 8.090 0.001
  Cognitive 60.99±30.23 64.99±22.14 65.00±19.70 0.048 0.064
  Social 63.66±23.75 55.67±18.64 41.65±13.16△※ 20.11 0.001
Symptom scales
  Fatigue 50.72±24.08 49.71±21.22 57.36±18.57 1.883 0.156
  Pain 25.80±20.09 31.67±21.09 38.67±22.41 5.108 0.020
  Nausea and vomiting 23.52±17.45 25.42±16.43 34.99±15.92△※ 9.050 0.001
Specific items reflecting symptoms and economic conditions
  Dyspnoea 50.67±34.51 37.33±26.65* 40.66±25.47 2.836 0.062
  Insomnia 35.78±30.06 46.33±25.50* 46.67±24.30 3.493 0.033
  Appetite loss 37.28±26.36 47.65±27.32* 68.68±23.73△※ 16.44 0.003
  Constipation 29.33±21.23 37.66±28.59 46.00±30.43△※ 3.453 0.043
  Diarrhea 32.92±23.65 35.00±25.85 34.92±26.47 0.182 0.785
  Financial impact 39.83±30.60 42.26±32.23 55.99±33.52△※ 3.776 0.031
Global quality of life 58.65±21.77 54.32±16.62 45.69±14.22 7.113 0.001