3.

热化组（TP化疗联合热疗）与单独化疗组（TP化疗）疗效比较的meta分析

Meta analysis of efficacy and safety for patients with NSCLC treated with TP Thermo-Chemotherapy and TP Chemotherapy alone

Outcome	Included studies	(TP) TCT			(TP) CT			Heterogeneity		Statistical method	Result of meta-analysis
		n	N		n	N		I2	P		OR (95%CI)	P
TP: paclitaxel and cisplatin.
Total effective rate	8[5-9, 12, 13, 15]	137	245		79	244		0	0.93	OR (M-H, Fixed, 95%CI)	2.74 (1.88-4.00)	< 0.000, 01
Improving rate of life quality	5[5-8, 12]	102	146		52	142		0	0.95	OR (M-H, Fixed, 95%CI)	4.15 (2.52-6.85)	< 0.000, 01
Myelosuppression	4[8, 9, 13, 15]	77	129		83	132		0	0.70	OR (M-H, Fixed, 95%CI)	0.88 (0.53-1.47)	0.63
Gastrointestinal reaction	3[8, 13, 15]	65	79		68	82		0	0.84	OR (M-H, Fixed, 95%CI)	0.98 (0.42-2.29)	0.96
Diarrhoea	3[8, 13, 15]	21	79		20	82		0	0.82	OR (M-H, Fixed, 95%CI)	1.13 (0.56-2.32)	0.73
Neurotoxicity	3[8, 13, 15]	41	79		41	82		0	0.86	OR (M-H, Fixed, 95%CI)	1.14 (0.57-2.31)	0.71