4.

化疗联合热疗组与单独化疗组疗效与安全性比较的meta分析

Meta analysis of efficacy and safety for patients with NSCLC treated with Thermo-Chemotherapy and Chemotherapy alone

Outcome	Included studies	TCT			CT			Heterogeneity		Statistical method	Result of meta-analysis
		n	N		n	N		I2	P		OR (95%CI)	P
Improving rate of life quality	8[3, 5-8, 10, 12, 14]	184	250		108	250		0%	0.96	OR (M-H, Fixed, 95%CI)	3.84 (2.61-5.64)	< 0.000, 01
Myelosuppression	6[3, 8, 9, 11, 13, 15]	133	200		142	205		0%	0.81	OR (M-H, Fixed, 95%CI)	0.88 (0.57-1.37)	0.58
Gastrointestinal reaction	5[3, 8, 11, 13, 15]	115	150		120	155		0%	0.98	OR (M-H, Fixed, 95%CI)	0.98 (0.56-1.71)	0.93
Hepatic lesion	3[3, 8, 11]	21	101		20	103		0%	0.83	OR (M-H, Fixed, 95%CI)	1.09 (0.54-2.19)	0.82
Renal lesion	3[3, 8, 11]	14	101		14	103		0%	0.48	OR (M-H, Fixed, 95%CI)	1.02 (0.46-2.26)	0.96
Diarrhoea	4[3, 8, 13, 15]	30	119		26	122		0%	0.88	OR (M-H, Fixed, 95%CI)	1.26 (0.69-2.31)	0.45