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. 2011 Nov 20;14(11):858–864. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2011.11.05

3.

四种药物代谢酶多态性与化疗疗效的关系

The relationship between the polymorphisms of 4 kind enzymes and chemotherapy effect

Genotyping		Chemotherapy		X²	P
Genotyping		Response	No response	X²	P
^*P < 0.05.
GSTM1	Null	53	23	7.71	0.005^*
GSTM1	Non-null	23	28
CYP1A1	A	37	14	5.206	0.023^*
	B	29	26
	C	10	11
CYP2E1	A	41	28	0.661	0.719
	B	24	18
	C	11	5
CYP2D6	w/w	28	15	0.756	0.685
	w/m	23	17
	m/m	25	19