Fig. 5. Efficacy of anti-influenza polyclonal antibodies for treating H5N6/GZ14-infected mice.

Female 8-week-old BALB/c mice (n = 6) were intranasally infected with 2 MLD₅₀ (10 pfu) of H5N6/GZ14. One day later, the mice were treated with an intraperitoneal injection of either 1 or 3 mg of anti-influenza IgG/mouse. The mock-treated mice received an intraperitoneal injection of 3 mg of purified unrelated IgG. a The body weights were measured every other day. The results from each group and each time point are expressed as the mean ± SD. b Survival of infected mice. Mice were euthanized when body weight loss exceeded 25% of the original weight